[1] : The Collaborative International Dictionary of English v.0.48

sophisticate \sophis"ticate\, sophisticated
\sophis"tica`ted\, a.
   adulterated; not pure; not genuine.
   1913 webster

         so truth, while only one supplied the state,
         grew scare and dear, and yet sophisticate. --dryden.
   1913 webster

[2] : The Collaborative International Dictionary of English v.0.48

sophisticate \sophis"ticate\, v. t. imp.  p. p.
   sophisticated; p. pr.  vb. n. sophisticating. ll.
   sophisticatus, p. p. of sophisticare to sophisticate.
   to render worthless by admixture; to adulterate; to damage;
   to pervert; as, to sophisticate wine. --howell.
   1913 webster

         to sophisticate the understanding.       --southey.
   1913 webster

         yet butler professes to stick to plain facts, not to
         sophisticate, not to refine.             --m. arnold.
   1913 webster

         they purchase but sophisticated ware.    --dryden.
   1913 webster

   syn: to adulterate; debase; corrupt; vitiate.
        1913 webster sophisticate
see also:
sophisticated sophisticating 

[3] : WordNet (r) 2.0

sophisticate
     n : a worldly-wise person syn: man of the world
     v 1: make less natural or innocent; "their manners had
          sophisticated the young girls"
     2: practice sophistry; change the meaning of or be vague about
        in order to mislead or deceive syn: twist, twist
        around, pervert, convolute
     3: alter and make impure, as with the intention to deceive;
        "sophisticate rose water with geraniol" syn: doctor, doctor
        up
     4: make more complex or refined; "a sophisticated design"
see also:
man of the world twist twist around pervert convolute doctor 
doctor up 

[4] : Moby Thesaurus II by Grady Ward, 1.0

18 moby thesaurus words for "sophisticate":
   blase, city slicker, cosmopolitan, cosmopolite, debase,
   disenchanted, disillusioned, doctor, knowing, load,
   man of experience, man-about-town, mondaine, slicker, weight,
   world-wise, worldly, worldly-wise

Sophisticate >> S Words
Sophisticate, definition of term: Sophisticate
sophisticate_pag1.html